Appearance：White or quasi-white powder

Assay：≥98%

Molecular structure：

Molecular weight：103.12

Molecular formula：C4H9NO2

CAS Number：144-90-1

Synthetic route：

Product application：

β-amino-isobutyric acid (BAIBA), a non-protein amino acid secreted by skeletal muscle through a peroxisomal proliferator activated receptor gamma coactivator 1-α (PGC-1α) dependent mechanism during regular exercise, has been found to be a novel endogenous protective muscle factor that regulates adipose tissue Browning. Improve insulin sensitivity and prevent obesity caused by a high fat diet.

The currently available literature identifies BAIBA as a powerful endogenous regulator of human metabolism. Elevated BAIBA caused by prolonged physical exercise or genetic polymorphism may favor body fat mass, plasma lipoprotein levels, insulin sensitivity, inflammatory response, and may favor arterial walls.

Intervention studies in mice and results obtained in cell culture models and human cohorts have demonstrated a novel function of the non-protein amino acid BAIBA - it is involved in the regulation of carbohydrate and lipid metabolism. In particular, BAIBA reduces the amount of fat in the body, increases insulin sensitivity, favorably affects lipid metabolism, and reduces inflammatory responses.

BAIBA, or beta-amino-isobutyric acid, is an amino acid produced during exercise (" exercise-induced muscle factor ") that is not naturally present in the genetic code of any organism - it is formed when thymine or valine is broken down.

This means that BAIBA, although an amino acid, is not a component of proteins, but is instead used as a signaling molecule in the body. Because of this, consuming it won't help with muscle mass development as much as traditional essential amino acids (typically used for recovery during or after exercise), but it may hold promise for fat reduction and weight loss.

References：

⑴BAIBA: Weight Loss Ingredient Coined “The Exercise Molecule”

⑵Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid

Metabolism - PubMed (nih.gov)

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