What is HMB-Ca?

HMB-Ca, or calcium beta-hydroxy-beta-methylbutyrate, is a dietary supplement derived from the amino acid leucine. It is commonly used to promote muscle growth and reduce muscle breakdown, particularly beneficial for athletes and older adults looking to maintain muscle mass.

Uses and Benefits

Research suggests HMB-Ca can help increase muscle mass and strength, particularly in those starting exercise programs or experiencing age-related muscle loss. It is widely available as an over-the-counter supplement, often taken to enhance athletic performance and support recovery.

Applications and Research

HMB-Ca is widely used in dietary supplements, particularly for enhancing muscle mass and strength. Research, such as studies in the British Journal of Nutrition, indicates it improves HMB clearance in plasma compared to free acid forms, with peak plasma levels around 60-120 minutes post-ingestion

It is effective in reducing muscle catabolism and promoting fat-free mass, especially in older adults and those initiating training programs

The Relationship with BHB

According to a study published in PMC, it seems likely that there is a metabolic connection between HMB Ca and BHB Calcium, as studies have shown that taking HMB can lead to increased levels of BHB in the body. This suggests HMB may be converted to BHB through liver metabolism, though the exact pathway is complex and still under research. This unexpected detail highlights how supplements can influence broader metabolic processes beyond their primary use.