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Acute Supplementation of Beta‐Hydroxybutyrate Increases Visual Cortical Excitability in Humans
Cate:News Center Time:2026-02-09
Exogenous ketones, such as #BHB salts or esters, elevate blood #ketone levels (e.g., βHB), providing an alternative brain fuel to glucose. The brain uses ketones efficiently during energy stress, potentially stabilizing metabolism, reducing oxidative stress, and modulating neural excitability.
A 2025 study in healthy adults showed that acute BHB supplementation significantly increased steady-state visual evoked potential (SSVEP) amplitude and resting alpha power, indicating enhanced visual cortical excitability and stronger EEG signals.
And SSVEP is a common #BCI method, so higher amplitude could directly boost signal strength and detection accuracy. Research suggests that non-invasive brain-computer interfaces (BCIs) primarily use alpha (8-13 Hz) and beta (13-30 Hz) brain waves, especially for motor imagery and steady-state visually evoked potential (SSVEP) applications.
Ketones also stabilize energy supply, bypassing glucose limitations and reducing ROS, which could minimize fluctuations in neural activity and EEG variability. This might enhance signal stability across sessions, especially during prolonged BCI use when glucose dips (e.g., fatigue).